I have written about long-term health effect concerns of the mRNA vaccines, particularly of autoimmune disorders (SARS-CoV-2 Vaccines). The following video (30:56 minutes) is an interview of a front-line doctor in British Columbia, practising in a small enough community that he can get a good picture of the side effects of the Moderna vaccine used in his community.

It is important to understand that the Moderna and Pfizer products are not traditional vaccines but what many call ‘gene therapies’. Indeed the research leading up to the Moderna vaccine was focused on genetic manipulation of genes to fight cancer and is described by Moderna as an “operating system” (emphasis added):

Recognizing the broad potential of mRNA science, we set out to create an mRNA technology platform that functions very much like an operating system on a computer. It is designed so that it can plug and play interchangeably with different programs. In our case, the “program” or “app” is our mRNA drug – the unique mRNA sequence that codes for a protein.

Source: Moderna. mRNA Platform: Enabling Drug Discovery & Development.

We have no long-term studies of the side-effects of this technology. The current global experiment using widespread vaccination without any design criteria, data collection, or result analysis, means that the reports by front-line doctors such as Dr. Charles Hoffe in this video, are the only warning that we may get of possible massive health implications of the vaccine in the future.

Autoimmune disorders can take months to years to manifest. Dr. Hoffe talks about neurological impacts that he has observed that may have an autoimmune component. He discusses other possible side effects such as female sterility due to pathogenic priming by the vaccines.

On the neurological front, I just cam across a paper by Dr. J.B. Classen who raises a concern that the vaccines may activate certain pathological prions (read the article by Weiler to learn about prions[2]) leading to ALS, Alzheimer’s and other possible degenerative disorder.

The RNA sequence of the vaccine as well as the spike protein target interaction were analyzed for the potential to convert intracellular RNA binding proteins TAR DNA binding protein (TDP-43) and Fused in Sarcoma (FUS) into their pathologic prion conformations. The results indicate that the vaccine RNA has specific sequences that may induce TDP-43 and FUS to fold into their pathologic prion confirmations.

The folding of TDP-43 and FUS into their pathologic prion confirmations is known to cause ALS, front temporal lobar degeneration, Alzheimer’s disease and other neurological degenerative diseases. The enclosed finding as well as additional potential risks leads the author to believe that regulatory approval of the RNA based vaccines for SARS-CoV-2 was premature and that the vaccine may cause much more harm than benefit.

Classen JB (2021).

You do need some serious biomedical background to understand this in detail. It merely identifies the proteins associated with vaccine activity and their cellular pathways that the author says are of concern.

It should be noted that this is raised as a serious concern requiring more extensive research and study, but not a confirmation that such prion activity is generated. However, one should give serious attention to these issues before taking an mRNA vaccine.


As an aside, I’ve been trying to figure out how to embed videos from Rumble and other platforms not supported by WordPress – at least through their Gutenberg editor. By turning the editor off, adding the link to the embed code to this article, and then restoring the editor, I seem to have figure out a clunky way to do it.


This frank admission has cost the doctor significant income and deprived his community of essential services: BC doctor stripped of ER shifts after raising COVID vaccine side effect concerns.


  1. Classen JB. COVID-19 RNA Based Vaccines and the Risk of Prion Disease. Microbiol Infect Dis. 2021; 5(1): 1-3. PDF.
  2. Weiler N. Alzheimer’s Disease is a ‘Double-Prion Disorder,’ Study Shows.


I started a blog in 2011 called The POOG, an acronym for "pissed off old guy". This is the current incarnation.


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